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Chase, H
Because of their popularity, many GLP-1 RAs like Ozempic and Wegovy are experiencing supply shortages
Given that dietary fibers structure varies by source and influences its function, and considering that fibers from different sources have different effects on constipation (17), the practical application of dietary fiber as a treatment for severe constipation is not satisfactory
Weeks 1-4: 2mg once weekly Weeks 5-8: 4mg once weekly Weeks 9-12: 8mg once weekly Week 13 onward: 12mg once weekly (maintenance) Total escalation time spans 12 weeks, slower than some competitors but necessary given the triple-receptor mechanism
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