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Moreover, GLP-1RA negatively influences the expression of peroxisome proliferator-activated receptors (PPARs), leading to a downregulation of proteins associated with lipid metabolism (37, 41, 42)
By Lana Pine | Published on July 6, 2026 Fact checked by: Afton Woodward 4 min read GLP-1 receptor agonists like semaglutide and tirzepatide have helped millions of people lose significant weight and better manage blood sugar
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