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Cardiovascular Outcomes Trials: History, Rationale, and Revelations The FDAs 2008 guidance mandated long-term CV safety assessments, a response to earlier safety signals and underpowered trials
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Yet, in many countries the devices being used to deliver GLP-1s are the same for both the weight loss and T2D populations and, in many cases, were originally designed for delivering insulin, such as Novo Nordisks FlexTouch pen (Wegovy, semaglutide) or Eli Lillys KwikPen (Mounjaro, tirzepatide) outside the US
What the research tells us How long will I continue to lose weight on Mounjaro
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