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Inject subcutaneously at a clean, rotated site abdomen, thigh, or upper arm For how to manage any side effects during titration, see our [semaglutide side effects guide](/guides/semaglutide-side-effects-how-to-manage)
Place the needle directly into the sharps container after usenever into regular household trash
By day 10, I was consistently leaving 1520% of my usual lunch portion on the plate without effort
Higher concentrations require smaller injection volumes, which can be more comfortable but require more precise measurement
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