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Does it cause functional impairment
Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers
This is also the phase where lifestyle habits become increasingly important
The effect of DPP4 antagonism was studied in models of myocardial ischemia/reperfusion (I/R) and infarction in normoglycemic and hyperglycemic animal models of CV disease by genetic deletion of DPP4 or by using DPP4i
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