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Novo Nordisk launched Wegovy (semaglutide) in India as a once-weekly GLP-1 receptor agonist for chronic weight management in adults with obesity or overweight-related health conditions, entering the market ahead of its patent expiry to counter competition from Eli Lillys Mounjaro
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In vitro characterization is classically done on cloned human receptors expressed in cell lines (HEK293, CHO) via cAMP measurements (ELISA, FRET) or beta-arrestin recruitment (BRET, NanoBiT)
Since excess weight is now understood as a chronic condition, ongoing treatment is often necessary to maintain results and support a healthy lifestyle
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