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All storage temperature, beyond-use date, and handling instructions must come from the trial sponsor's pharmacy manual or the IMP label not from general peptide guidance

Compounded semaglutide is not FDA-approved and should only be used under the supervision of a licensed provider

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These figures reflect the specific study population - patients who completed at least 365 days on the protocol - and may not represent real-world discontinuation patterns or outcomes for all patients who begin the program