Since LAL is involved in the degradation of lysosomal cholesterol esters and TAGs, in case of mutated LAL, lipid accumulation is triggered in the liver, spleen, adrenal glands, bone marrow, lymph nodes, macrophages throughout the body, and intestinal villi, in particular
Plant Cell Environ 33:453467 Mittler R (2002) Oxidative stress, antioxidants and stress tolerance
On the other hand, this compound showed a reduction of TC cell viability, proliferation, and some aspects related to the metastatic process in vitro
This makes it particularly useful in experiments assessing cell survival, tissue growth markers, myoblast proliferation, and metabolic signaling under controlled laboratory conditions