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Deficiency in the level of activity of glucose-6-phosphate dehydrogenase (G6PD) is the basis of favism, primaquine (an anti-malarial drug) sensitivity and several other drug-sensitive hemolytic anemias, anemia and jaundice in the newborn, and chronic nonspherocytic hemolytic anemia

Some of these by-products can also pose potential toxicity

Rectangular boxes represent the substrates that can vary in the model, and the ellipses contain the acronyms of the enzymes that catalyze particular reactions

Clinical and in vitro studies demonstrate that GHK-Cu significantly increases the production of collagen types I and III, elastin, and glycosaminoglycanskey structural components responsible for skin firmness and elasticity (Maquart et al., 1988