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As a member of the class B GPCR family, GCGR is involved in various physiological processes and is a valuable drug target for a range of diseases, including diabetes, metabolic syndrome, osteoporosis, migraine,depression, and anxiety[2], with a particularly important role in the treatment of type 2 diabetes
The peptide modulates dopamine and serotonin systems, contributing to improved neuromuscular coordination and nerve conduction in animal studies, supporting interest in neurological repair research
As a dual agonist, tirzepatide (GLP-1 + GIP) continues to outperform semaglutide in weight loss and metabolic control, setting a new bar for combination therapies
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