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Gene expression studies confirm direct effects on pathways controlling hair growth, and the combination of preclinical efficacy plus clinical success in topical applications supports the rationale for injectable use

During the mean observation period of 3.3 years, semaglutide at 2.4 mg per week resulted in a mean weight loss of 9.39% from baseline and a 20% reduction in the risk of MACE (HR 0.80, 95% CI 0.720.90), especially a 28% reduction in the risk of myocardial infarction (HR 0.72, 95% CI 0.610.85), compared with that in the placebo group

10.3389/fimmu.2021.652252 Front Immunol