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Answer: To relieve constipation on semaglutide or tirzepatide, increase fluid intake, gradually add soluble fiber (such as psyllium husk), remain physically active, and use an osmotic laxative (such as polyethylene glycol) if needed
It potentially selectively attaches to ghrelin receptors in laboratory models during clinical trials
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For someone on a GLP-1 medication where transit time is already extended, this can make the difference between a comfortable daily bowel movement and going 3-4 days without one
