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Abbreviations AMH: Anti-Mllerian hormone AMPK: AMP-activated protein kinase ANSD: Androstenedione AT1: Acupuncture Table 1 AT2: Acupuncture Table 2 AT3: Acupuncture Table 3 AT4: Acupuncture Table 4 BMI: Body mass index BSTJF: Bu-shen-tian-jing formula Chti-TPP: Chitosan-tripolyphosphate CNS: Central nervous system COCPs: Combined oral contraceptive pills CRP: C-Reactive Protein CYP17A1: Cytochrome P450 17-hydroxylase DHEA: Dehydroepiandrosterone DHEAS: Dehydroepiandrosterone sulfate DHT: Dihydrotestosterone FSH: Follicle-stimulating hormone GLP-1Ras: Glucagon like peptide-1 receptor agonists GLUT4: Glucose transporter type 4 GnRH: Gonadotropin-releasing hormone HDL: High density lipoprotein HHOA: Hypothalamus-hypophysis-ovarian axis HMG-CoA: 3-hydroxy-3-methylglutaryl coenzyme A hMG: Human menopausal gonadotropin HOMA-IR: Homeostatic Model Assessment for Insulin Resistance INSR: Insulin receptor IR: Insulin resistance IVF: In vitro fertilization LDL: High density lipoprotein LH: Luteinizing hormone LncMEG3: Long non-coding RNA MEG3 LncRNA: Long non-coding RNA MDA: Malondialdehyde NGF: Nerve growth factor NLRP3: NOD-like receptor pyrin domain-containing protein 3 PCOS: Polycystic ovary syndrome PPARs: Peroxisome proliferator-activated receptors RCT: Randomized controlled trial SHBG: Sex hormone-binding globulin SNEDDS: Self-nanoemulsifying drug delivery system TT: Tribulus terrestris L VAC: Vitex agnus-castus L YAP-1: Yes-associated protein1 References Di Lorenzo M, Cacciapuoti N, Lonardo MS, et al