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None of them evaluated the long-term toxicity, nor did they conduct gene knockdown or overexpression experiments to verify the regulatory mechanisms of natural products (Wang et al., 2023c
They were also less likely to have heart disease, which may have led to their lower risk
Su, V., Nakagawa, R., Koval, M
found that Astragalus mongholicus not only reduces -synuclein aggregation in the striatum but also decreases Proteobacterias relative abundance in PD models (Wan et al., 2022), indicating Astragalus mongholicus inhibits TMAO production while reducing -syn aggregation leading to PD
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