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2025, Jul, 29;11(1):351 Florencio LL, Fernndez-de-Las-Peas C

While acknowledging that GLP-1 agonists have revolutionized the way diabetes and obesity are managed and play an important role in the care of many patients, the commentors ask, Will healthcare professionals prescribe these medications because they lead to a decreased risk of AMD

(Thus, our goal was to design a peptide agonist that overcomes these shortcomings and compare glucoregulation/appetite control driven by the incorporation of Y1-R/Y2-R agonism, a property not shared by tirzepatide incorporation

For obesity innovators, 2025 will mark a turning point as we move past peak hype and see the beginning of more conventional competitive dynamics gradually establish themselves in the AOM market