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164 Notably, larger doses or longer durations of GLP-1RA therapy have been associated with an increased risk of cholelithiasis, 165 a primary risk factor for AP

Fix the metabolic dysfunction, whether through weight loss, direct receptor effects, or both, and the brain benefits

The week-4 review was already on the calendar as the dose-escalation visit, and since that is the labelled point for moving from 3 to 7 mg, we used it to recheck his mood before stepping up rather than because anything had prompted concern