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van Poppelen, N
Choline Choline is an essential nutrient that is necessary for controlling the buildup of fat and cholesterol in the body
As such, the model was used to simulate how long it would take pharmacologically and toxicologically relevant concentrations of doxorubicin to yield a 70% reduction in GSH concentration, indicative of impaired cellular antioxidant defence, protein binding and cell death 19
4) Lean on medical guidance This is the phase where clinician input matters mostespecially around dose titration and expectations
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