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137(5): 432-439 Natalizia A, Casale M, Guglielmelli E, et al
Participants who received the highest dose of orforglipron, 36 milligrams, lost 11.2% of their body weight - about 25 pounds on average - over more than 16 months
The challenge in evaluating GLP-1 safety lies in disentangling drug effects from underlying disease risk
These operational hurdles play into the niche of the industry and make it less accessible to the wider public
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