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But they work better as a team than any one of them alone
Furthermore, NADPH is replenished by the isocitrate dehydrogenase (IDH1/IDH2) branch of the citric acid cycle (TCA cycle), malic enzyme (ME1), and one-carbon metabolism (such as the folate cycle) depending on cell type or nutritional status
In the dynamic interaction between immune effector cells and tumor cells, carnitine can confer resistance to immune cell killing to tumor cells through carnitine palmitoyltransferase 1 A (CPT1A)-mediated FAO [64]
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