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Papaetis GS, Filippou PK, Constantinidou KG, Stylianou CS (2020) Liraglutide: new perspectives for the treatment of polycystic ovary syndrome

The protective effects of GLP-1 RAs against cardiovascular events have been demonstrated in several studies, thus supporting their application in patients with heart failure with preserved ejection fraction and DM2 (28)

For these individuals, introducing supplemental sulfur donors like glutathione or N-Acetyl-l-Cysteine (NAC) can sometimes trigger paradoxical mast cell reactions, causing symptom flares, hives, or worsened tachycardia