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In other patients with vitamin B12 deficiency, the duration of therapy and route of administration will depend upon the cause and whether or not it is reversible

Because of how vitamin B12 is absorbed, the most common risk factors for B12 deficiency are: Genetic susceptibility : Some people genetically produce less intrinsic factor and stomach acid needed for B12 absorption

thus, more studies are needed to establish optimal dosing regimens and identify which combination approaches provide the most meaningful dermal benefits, especially in aging women