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A hallmark of autophagy is the generation of double-membraned autophagosomes, which subsequently fuse with either an endosome or a lysosome to enable degradation (143)

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Effects of B-cell directed therapy on the preclinical stage of rheumatoid arthritis: the PRAIRI study

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Zepbound (tirzepatide) is a newer medication that acts as a dual agonist

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