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It is still debatable whether or not small molecules of ferroptosis stimulants can be employed to specifically kill cancer cells with anomalies in the RASRAFMEK pathway [46, 52]

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This work is also limited by the demographics of our participants, who were predominantly white, tended to be young, and had high income and educational attainment

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GSH depletion can trigger ferroptosis, which has been exploited in cancer treatments [17], and supplementation with GSH is utilized by glutathione peroxidase 4 (GPX4) to prevent lipid peroxidation, in turn inhibiting ferroptosis

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Abbreviations CoA, Coenzyme A

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